Lyme DiseaseHigh Risk
Tick: Blacklegged ticks
Region: Northeast, upper Midwest, mid-Atlantic
Symptoms: Bull's eye rash, fever, fatigue, headache
Rocky Mountain Spotted FeverHigh Risk
Tick: Dog ticks, Rocky Mountain wood ticks
Region: Western states
Symptoms: Spotted rash, fever, chills, headaches, muscle aches, nausea, neurological problems
AnaplasmosisHigh Risk
Tick: Blacklegged ticks, Western blacklegged ticks
Region: Northeast, upper Midwest, West Coast
Symptoms: Fever, chills, headaches, muscle aches, nausea, vomiting, diarrhea
EhrlichiosisModerate
Tick: Lone star ticks
Region: Southern states, Gulf, mid-Atlantic
Symptoms: Fever, muscle aches, headaches, nausea, vomiting, diarrhea, cough, skin rash
BabesiosisModerate
Tick: Blacklegged ticks
Region: Northeast, upper Midwest
Symptoms: Infects red blood cells similar to malaria
Powassan DiseaseHigh Risk
Tick: Blacklegged ticks
Region: Northeastern US
Symptoms: Fever, vomiting, headache, weakness. Can lead to encephalitis, meningitis, death
Bourbon VirusHigh Risk
Tick: Various ticks
Region: Midwest
Symptoms: High fever, headache, muscle/joint pain, fatigue, diarrhea, vomiting
Heartland VirusModerate
Tick: Lone star ticks
Region: Midwest, southern Gulf states
Symptoms: Fever, fatigue, muscle/joint pain, headache, nausea, diarrhea (2 weeks to appear)
Colorado Tick FeverLower Risk
Tick: Rocky Mountain wood ticks
Region: Western states
Symptoms: Fever, fatigue, chills, headaches, body aches, sore throat, vomiting, skin rash
TularemiaModerate
Tick: Dog ticks, wood ticks, lone star ticks
Region: Throughout US
Symptoms: Fever, chills, fatigue, muscle pain, cough, sore throat, vomiting, diarrhea
Southern Tick Associated Rash Illness (STARI)Moderate
Tick: Lone star ticks
Region: Southeast, south-central states
Symptoms: Bull's eye rash, fatigue, muscle pains, fever, headache (similar to Lyme)
Tickborne Relapsing FeverModerate
Tick: Various tick species
Region: Western and southwestern states
Symptoms: High fever that fades and returns, headache, muscle/joint pain, chills, vomiting